The science behind the gut-brain connection
The answer to a healthier, more vibrant mind might be closer than you think—your gut. Uncover the groundbreaking link between gut health and mental wellness.
LEARN MOREGut microbiota and brain function
The Gut-Brain Axis is a revolutionary concept linking the gut and mind. This two-way connection influences mental health, stress, and digestion, with emerging research highlighting the role of gut microbiota in these interactions.
- The gut produces 90% of serotonin
- Probiotics support gut-brain harmony
- A healthy diet boosts the gut-brain axis
- Balanced gut bacteria improve resilience
- The gut and brain share a direct nerve link

The proven impact of NU10 probiotics
52%
Achieved greater mental clarity and emotional strength, creating a foundation for healthier daily habits and relationships.
40%
Experienced reduced nervousness, creating a sense of calm that positively influenced their overall mental well-being.
28%
Felt re-energized and free from mid-day slumps, allowing them to enjoy their day with greater vitality and focus.

A Combination of Apple Vinegar Drink with Bacillus coagulans Ameliorates High Fat Diet-Induced Body Weight Gain, Insulin Resistance and Hepatic Steatosis
PMID: 32825073 | PMCID: PMC7551919 | DOI: 10.3390/nu12092504

Optimization of Spore Production in Bacillus coagulans Using Response Surface Methodology Approach
PMID: 38526660 | DOI: 10.1007/s12010-024-04934-2

The spores of various Bacillus species such as Bacillus coagulans and Bacillus subtilis, have significantly improved viability and stability under harsher conditions during heat processing.
PMID: 39123635 | PMCID: PMC11312092 | DOI: 10.3390/foods13152444
Summary Clinical Research on Bacillus coagulans NU10
Evidence-based innovation for immune and mood support
At Nutris We Care About You S.L. / Advanced Nutraceuticals BV, we believe that true innovation in probiotics starts with solid science.
Our proprietary probiotic strain, Bacillus coagulans NU-10, has been evaluated in a randomized, double-blind, placebo-controlled clinical study designed to assess its effects on immune modulation and overall well-being.
The study — registered under ISRCTN16720091 — was conducted at a leading clinical center in Barcelona, Spain, with full ethics approval (ref. 2021/81-DER-HUSC).
It investigated the daily use of Bacillus coagulans NU-10 (5 × 10⁹ CFU) over 90 days in healthy adults.
Key findings ¹
- Supports immune balance: Participants taking B. coagulans NU-10 showed statistically significant improvements in immune markers compared with placebo (IgA, IgG, IFN-γ, and total leukocyte count).
- Promotes vitality and emotional well-being: Quality-of-life scores (SF-36) demonstrated positive changes in domains related to mental health and vitality.
- Excellent tolerability: No adverse events were reported; the strain showed robust acid, bile, and heat stability and no transferable antibiotic resistance (esto no está relacionado con el estudio, lo eliminaría).
¹ Study results on file with Nutris We Care About You S.L. / Advanced Nutraceuticals BV; the full dataset remains proprietary pending peer-review publication.
Why it matters
Emerging science on the gut–brain and gut–immune axes suggests that balanced intestinal microbiota play a key role in both physiological and emotional resilience.
NU-10’s clinically tested profile makes it an ideal probiotic for next-generation formulations targeting mood, immune health, and overall vitality.
Scientific integrity
Nutris We Care About You S.L. / Advanced Nutraceuticals BV ensures all clinical work is performed under Good Clinical Practice (GCP) standards and independent ethical review.
We maintain full transparency by publicly registering every human trial while safeguarding commercially sensitive details until peer-review publication.

Backed by science
Discover the groundbreaking research behind NU10 probiotics. This whitepaper explores the science of Bacillus coagulans, its stability, and its proven health benefits. Download now to see why NU10 is setting the standard in probiotics.

